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Du Toit won the role of Izzy Davies in the Channel 4 Soap Opera Hollyoaks after an open audition – beating 40,000 hopefuls. She left the show in 2004 after four years filming in Liverpool. In November 2011, Du Toit made an appearance in Coronation Street as Jenny, the ex-girlfriend of Matt Carter.

She married actor Rafe Spall in 2010, and they live in West Kensington, London. Their first child, a daughter named Lena, was born in 2011, and in November 2012 their second, a son named Rex. They also have a third child, another son, born in 2015.

Elize du Toit was born in Grahamstown, South Africa, the second of four children, to an artist mother and an orthodontist father. She spent most of her childhood in Pretoria. She moved to Berkshire, United Kingdom, in December 1994, where she attended Wellington College, completed her A-levels – attaining straight As in English, French, history and history of art – and was a member of Reading's Progress Theatre. She studied history at the University of Edinburgh and performed with the Edinburgh University Theatre Company.

Elize du Toit (born 21 February 1980) is a South African-born English actress best known for playing the role of Izzy Davies in the Channel 4 soap opera Hollyoaks from 2000 to 2004, with a brief return in 2007.