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Denton was Executive Director of Great Ormond Street Hospital Children's Charity (GOSHCC) from 2006 for three years, and then chairman of the charity until 2012. In December 2008 he was appointed trustee and chairman of the African Orphan’s charity Sentebale ['Forget Me Not' in Sesotho], set up in April 2006 by Prince Seeiso of Lesotho and Prince Harry to help vulnerable children and young people in Lesotho, particularly those who have been orphaned as a result of HIV/AIDS.

In the early 1990s Denton formed the VFN (Virtual Film Network) based in Shoreditch, set up to promote new media skills amongst the unemployed. In 2006 Denton became involved in the ‘Life & Deaf’ Speech and Language Therapy project, which aims to develop Deaf children’s self-esteem.

Career summary: Charles Denton began his career during the 1980s in financial services with Charles Sturge & Co. In 1989 he joined Molton Brown where, until its 2005 sale to Japan's Kao Corporation, he worked in various roles including Sales & Marketing Director, Chief Executive and Deputy Chairman. From 2007 to 2008 he was Deputy Chairman of electronic commerce group, ArgentVive plc. In 2009, Denton became chairman of the award-winning advertising agency Fold7. The agency was set up in 1995 specialising in advertising and brand strategy. In February 2011 RBS Special Opportunities Fund backed Denton in acquiring the New York brand Erno Laszlo.

Charles James Denton (born 20 February 1965) is an English entrepreneur who has served as chief executive of a number of business enterprises and held volunteer positions within various charitable organizations. Educated at Millfield School in the Somerset village of Street.